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Project of department of dermatology
University Gugliemo Marconi, Rome, Italy
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Systemic medication treatment

Oral steroids and other immunosuppressants


Oral steroid minipulse therapy

Studies on systemic steroids have been sparingly reported in the literature. Pulse therapy refers to the intermittent administration of large (suprapharmacological) doses to enhance the therapeutic effect and reduce the side-effects of a particular drug. Systemic steroids can arrest the activity of the disease, but are not effective in repigmenting stable vitiligo. Moreover side-effects associated with long-term use of daily systemic corticosteroids contraindicate their common use.

Other immunosuppressants and biologics

Immunosuppressants other than oral steroids have been evaluated in a limited number of studies. Anecdotal reports also exist on the off-label use of some immunomodulating biologics in vitiligo.
 

Systemic antioxidants


Antioxidants for the treatment of vitiligo

If you have vitiligo, increasing intake of antioxidants may be the key to stopping the progression of the disease and even skin repigmentation.

It is experimentally demonstrated that keratinocytes obtained from vitiligo zones plates generate large numbers of superoxide anions - reactive oxygen species and nitric oxide. This is a known free radical toxic to melanocytes.

It is now known that patients suffering from generalized form of vitiligo has an imbalance between oxidant and antioxidant systems.

Appropriate means of food antioxidants in the treatment of vitiligo are the series of ViTiX. The products have no side effects and showed excellent good tolerability. ViTiX series contains powerful antioxidants that restore physiological levels of catalase activity.

ViTiX tablets are antioxidants in the form of a dietary supplement that first act directly in the source of free radicals. ViTiX tablets are first antioxidants that combine primary and secondary antioxidants.